4-Nitro Methanesulfonanilide

4-Nitro Methanesulfonanilide - Names and Identifiers

Name	4-Nitro Methanesulfonanilide
Synonyms	4-NITRO METHANESULFONANILIDE 4-Nitro Methanesulfonanilide N-(4-Nitrophenyl)MethanesulfonaMide Methanesulfonamide, N-(4-nitrophenyl)-
CAS	5825-62-7

4-Nitro Methanesulfonanilide - Physico-chemical Properties

Molecular Formula	C7H8N2O4S
Molar Mass	216.21
Density	1.525±0.06 g/cm3(Predicted)
Melting Point	186 °C
Boling Point	380.7±44.0 °C(Predicted)
pKa	6.14±0.10(Predicted)
Storage Condition	2-8°C

4-Nitro Methanesulfonanilide - Introduction

4-Nitro Methanesulfonanilide is an organic compound with the chemical formula C7H7N3O5S. It is a yellow crystalline powder.

Its properties are as follows:
1. Melting point: 156-157°C
2. Boiling point: about 408°C
3. Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, ether and chloroform.

4-Nitro Methanesulfonanilide are mainly used in biological research and drug synthesis. It is used as an intermediate in drug synthesis, for the synthesis of antibacterial drugs, etc.

The method of preparing 4-Nitro Methanesulfonanilide includes the following steps:
1. mesylation: reacting methanesulfonic acid (methanesulfonic acid) with thionyl chloride (sulfonyl chloride) to generate methanesulfonyl chloride (methanesulfonyl chloride).
2. electrophilic substitution: methanesulfonyl chloride reacts with aniline (aniline) under alkaline conditions to generate 4-Nitro Methanesulfonanilide.

4-Nitro Methanesulfonanilide should pay attention to safety during operation:
1. It is an irritant substance, contact with the skin or inhalation may cause irritation and discomfort. Therefore, appropriate personal protective equipment such as gloves, goggles and protective clothing should be worn during operation.
2. avoid contact with flammable substances, oxidants and strong acids and other incompatible substances to prevent dangerous reactions.
3. should be sealed in storage, and away from heat and fire sources.
4. If accidentally exposed or inhaled, go to the hospital for help immediately.

Last Update：2024-04-09 20:48:19